Embodiments of the present application relate to the technical field of cyber-physical systems, and in particular to a cyber-physical system wireless resource optimization method and system based on event triggering. The method includes : based on the bit error rate, obtaining the packet loss rate, the transmission power of the transmitter, and the cellular network Correspondence between selection probability; introducing an event trigger mechanism at the controller end to optimize the number of data transmissions between the controller and the actuator; analyze the stability of the closed-loop system after introducing the event trigger mechanism, and obtain the constraints that make the closed-loop system stable; construct a multi-objective optimization function using the constraint conditions as constraints; the genetic algorithm is used to solve the multi-objective optimization function, and the optimal trigger coefficient, optimal transmission power and optimal cellular network selection probability are obtained under the premise of ensuring system performance. The optimization method provided by this application can achieve the balance between communication energy saving, system performance and data transmission cost of unit-level CPS in heterogeneous wireless networks.