The invention discloses a multi-star point simulation precision positioning device, which includes : a star point plate, the surface of which is etched with star points corresponding to the simulated target star map; a mounting seat with a mounting hole on it, and the star point plate is coaxially installed in the mounting hole; the locking orifice plate is provided with a groove on one side that matches the mounting base. The bottom surface of the groove is provided with multiple through holes corresponding to the star points. Each through hole is equipped with an optical fiber collimator. The mounting base is installed in the groove to make the optical fiber collimator coaxial with the corresponding star point. According to the multi-star-point simulation precision positioning device disclosed by the invention, high-precision vertical installation between the optical fiber collimator and the star-point plate is realized, and the accuracy of star-point display positions in a simulation target star map and good transmission of a light source simulation effect are ensured by utilizing a mechanical structure